Low glutamate diet

[vergil96]

Do you know what it has to exclude? I don't find conclusive information on the internet. It's supposed to be helpful for autistics.

(title edited)

 

[tree]

Glutamine? Or glutamate?

 

[vergil96]

I'm not sure tbh

I think someone told me glutamine but meant glutamate? Anyway, the neurotransmitter apparently can be decreased through diet?

 

[tree]

Glutamine - Wikipedia


Glutamate (neurotransmitter) - Wikipedia

 

[vergil96]

I know, but I don't know which one is the one in the diet. Often chemical compounds aren't absorbed directly, but are metabolised to the ones someone needs or is sensitive to. Very rarely a neurotransmitter is consumed directly, but maybe here that's the case?

 

[tree]

Low glutamine diet

Spoiler

This *someone* who mentioned whatever it was they mentioned,
was that a medical care provider?

 

[vergil96]

This *someone* who mentioned whatever it was they mentioned,
was that a medical care provider?

Nope, someone else in an internet autism support group. A doctor would be more specific, I suppose.

Avoiding protein seems like a bad idea.

 

[vergil96]

Then it has to be glutamete

Allergy diet - glutamate low

?

 

[tree]

Can you go back to the place where you first heard/read
about whatever it was, and check?

 

[vergil96]

Glutamate, it looks like the google search gave me both and I came here with the wrong name

But I think we have already concluded that it was gluatmate and low glutamine isn't sensible?

 

[Kayla55]

Glutamate is an amino acid that is produced in the body and also occurs naturally in many foods. Monosodiumglutamate (MSG) is the sodium salt of glutamic acid and is a common food additive. MSG is made from fermented starch or sugar and is used to enhance the flavor of savory sauces, salad dressings, and soups.

Both natural glutamate and monosodium glutamate are metabolized in the body using the same processes. Even though glutamate exists naturally in the body and in healthy foods, many people worry that excessive glutamate consumption can lead to health problems.

 

[Kayla55]

In your brain, glutamate is the most abundant excitatory neurotransmitter. An excitatory neurotransmitter excites or stimulates a nerve cell, making it more likely that the chemical message will continue to move from nerve cell to nerve cell and not be stopped. Glutamate is essential for proper brainfunction.

Glutamate is recycled and made by glial cells in your brain. Glial cells convert “used” glutamate to glutamine, which is converted back again into glutamate when delivered back to the terminal area of nerve cells.

glutamic acid. Both are naturally in food such as cheese, tomatoes, mushrooms and meat. Glutamate is not related to gluten. The U.S. Food and Drug Administration, also called FDA, lists MSG as a food ingredient that's safe to eat in typical amounts.

 

[Kayla55]

Do you know what it has to exclude? I don't find conclusive information on the internet. It's supposed to be helpful for autistics.

(title edited)

High Glutamate Foods

 

[Kayla55]

I skimmed through wdbMD diet list and reason it could be recommended is because processed meat, probably unatursl spices with MSG, avoiding moldy cheese.

Carnivore diet can be modified to contain more fat, chicken livers good option (note factory species will retain excess pesticides in liver so re-poisoning yourself) eggs but full antibiotics or bad eggs full salmonella.
Cheap efficient carnivore additive, livers. Also reduces constipation(?) On carnivore with /without the veg

Avoid Asian food if you don't know what additives are, as it can be worse than Germanic influenced western diet.
Bacon is a processed meat, even if it's Asian fusion on skewers with cherries.
Now cheese grillers and salami (depends how made but avoid altogether) ask for sodium free soya, and sauces as webMD suggests are worse than west.
Instead marinade must make own with apricot jam which no, um isn't same. This is good glaze for pork if you not using spices. And finishes eisbein well, I'm not spiced version so honey glaze, garlic and dried chilli makes it good carnivore diet, modified very fatty.
Other health choices: avoid teriyaki prawns, ask olive oil and garlic grill. Avoid corn-flakes and weetbix. I enjoy pumpernickelbread but no rye breads. German diet isn't healthier, not for glutinous free people. This is my allergies restaurant Bacup: I do know what I'm doing. I only apply apple jelly as glaze once pork is cooked due to hearing of sugar, so this way it brows quick near end cooking time. (Sugar heated in marinade mix that as bad as many Asian sauces like oyster sauce)

Viennas or hot dogs were our favourite, long time ago stopped as my ex pretends not to notice cheese griller content. Even bratwurst contains gluten and pork bangers. Avoid sausage altogether.
I consider pork bangers to be healthiest however may also mix bit wheat.

 

[Neonatal RRT]

In some variants of autism, there can be an imbalance of glutamate (excitatory) and GABA (inhibitory) neurotransmitter. A literature review suggests there's little direct evidence that lowering dietary glutamine significantly alters brain glutamate levels or improves ASD symptoms. Glutamine is abundant in foods, and the body can synthesize it, so restricting intake may not effectively reduce brain glutamate. Moreover, glutamine is critical for gut health and immune function, with are often compromised in ASD.

Increasing GABA could enhance inhibitory signaling, potentially counteracting excessive excitation. GABA supplementation may help but is poorly absorbed through the blood-brain barrier.

Do some more research on the role of L-theanine and N-acetylcysteine (NAC) supplementation in ASD, as these modulate glutamate levels.

 

[vergil96]

Do some more research on the role of L-theanine and N-acetylcysteine (NAC) supplementation in ASD, as these modulate glutamate levels.

Do you have brands of those supplements to recommend? I ordered the only brand of NAC in the internet pharmacy in my country and it was rotten. It might be a problem with amino-acids in general that they require careful storage? I order in this pharmacy on a regular basis and I've never had similar problems with other supplements, so it's not that the pharmacy stores products in poor conditions. The brand might have had poor quality, it was cheap, directed at gym-goers, not thoroughly tested, not intended for medical use and it's not one of those that I usually buy and are effective. It was the only brand available, unfortunately, so I think I might have to order directly.

 

[Neonatal RRT]

Do you have brands of those supplements to recommend? I ordered the only brand of NAC in the internet pharmacy in my country and it was rotten. It might be a problem with amino-acids in general that they require careful storage? I order in this pharmacy on a regular basis and I've never had similar problems with other supplements, so it's not that the pharmacy stores products in poor conditions. The brand might have had poor quality, it was cheap, directed at gym-goers, not thoroughly tested, not intended for medical use and it's not one of those that I usually buy and are effective. It was the only brand available, unfortunately, so I think I might have to order directly.

FYI, that "rotten" smell, much like "rotten eggs" is supposed to be there. NAC has that odor because of the hydrogen sulfide on the molecule. Acetylcysteine

I happen to be using a brand called "NOW". 600mg w/selenium. 1 in the am, 1 in the pm.

BTW, selenium helps to detoxify heavy metals in the body, which seems to be a problem with some autistics. Research on the topic suggests that there can be excessive heavy metal level accumulation in autistics as compared to controls. Unclear what the mechanism is but seems to be a repeatable finding across the studies looking at this. Another topic, but relevant if you are looking to improve one's health within the context of autism.

https://www.amazon.com/s?k=nac+supplement+n-acetyl+cysteine&crid=1LJOXZ3IWSY0A&sprefix=NAc+S,aps,127&ref=nb_sb_ss_ts-doa-p_2_5

 

[vergil96]

Is L-theanine excitatory? I like tea, but I have issues with it, including green tea. I'm not sure if it contains so much caffeine or if it's theanine or a different substance, but it's much worse than strong coffee for me. It makes me feel unable to focus or even feel on edge when that happens or it might trigger me into OCD and other forms of anxiety. Apparently green tea raises serotonin and I have similar but stronger issues with SSRIs.

 

[Neonatal RRT]

Is L-theanine excitatory? I like tea, but I have issues with it, including green tea. I'm not sure if it contains so much caffeine or if it's theanine or a different substance, but it's much worse than strong coffee for me. It makes me feel unable to focus or even feel on edge when that happens or it might trigger me into OCD and other forms of anxiety. Apparently green tea raises serotonin and I have similar but stronger issues with SSRIs.

Inhibitory. It is a partial glutamate antagonist and/or modulator of glutamate receptors.

 

[vergil96]

FYI, that "rotten" smell, much like "rotten eggs" is supposed to be there. NAC has that odor because of the hydrogen sulfide on the molecule. Acetylcysteine

Oh, I see. So it wasn't rotten. It smelled like rotten eggs, yes.

BTW, selenium helps to detoxify heavy metals in the body, which seems to be a problem with some autistics. Research on the topic suggests that there can be excessive heavy metal level accumulation in autistics as compared to controls. Unclear what the mechanism is but seems to be a repeatable finding across the studies looking at this.

Seems useful.

Apparently certain metals are also excitatory for the nervous system, but given that heavy metals are poisonous for the brain too and kill neurons, I'm not sure what to make of the information. I just learnt it a few days ago that metals might be excitatory as well, so don't quote me on that.