Transgenic mice

[Kayla55]

About Pesticides and Reproductive Health

We know all this not through mice, but rather human exposure to pesticides. I'm not sure what researchers did find in experiments that we don't know or what is useful.

We already know about endocrine system and need for vitamin A

Question is do you believe autism has affected your sexuality, did you swap XY chromosone, do you think it's pesticides exposure.
Dr. Berg explains michondre and exposure pestides, poor diet and various factors leading to autism. Many speculating due XY reason it starts in the womb.

 

[Kayla55]

 

[Kayla55]

Can sexuality be perceived as ultimate disability?

 

[Kayla55]

HRP being quite buzz word in menopause treatments,
Hormones used in birth control....

Is any of this really new?

 

[Kayla55]

 

[Neonatal RRT]

About Pesticides and Reproductive Health

We know all this not through mice, but rather human exposure to pesticides. I'm not sure what researchers did find in experiments that we don't know or what is useful.

We already know about endocrine system and need for vitamin A

Question is do you believe autism has affected your sexuality, did you swap XY chromosone, do you think it's pesticides exposure.
Dr. Berg explains michondre and exposure pestides, poor diet and various factors leading to autism. Many speculating due XY reason it starts in the womb.

Q. Do you believe autism has affected your sexuality? A. No. Strongly heterosexual.

However, it is well-studied that a disproportionate amount of LGTBQ individuals are also on the autism spectrum. It is also well-studied that the perturbations in the maternal hormonal milieu (testosterone, estrogen, progesterone, and thyroid hormones) is a significant epigenetic risk factor for having autistic children. A common cause might being significantly overweight (fat cells cause estrogen dominance) and mothers over 35 (perimenopause). Older parents also have had increased or prolonged exposures to environmental toxins that affect the endocrine system, another potential contributor. Having said that, my parents were teenagers when I was born, so who knows.

Whether you are XX or XY, or XXY or something else is determined at conception, when sperm combines with egg. That determines whether you are a chromosomal male or female. What gender or sexuality you identify with is something else entirely and is more of a neurodevelopmental situation. How you present physically, is a combination of genetics, but also those environmental toxins and phytoestrogens that affect the endocrine system, particularly inhibiting testosterone and enhancing estrogens within the body. Significantly lower sperm counts and testosterone levels in young men. Little girls reaching puberty at 10-12 years old. These sorts of phenomena.

 

[Kayla55]

Q. Do you believe autism has affected your sexuality? A. No. Strongly heterosexual.

However, it is well-studied that a disproportionate amount of LGTBQ individuals are also on the autism spectrum. It is also well-studied that the perturbations in the maternal hormonal milieu (testosterone, estrogen, progesterone, and thyroid hormones) is a significant epigenetic risk factor for having autistic children. A common cause might being significantly overweight (fat cells cause estrogen dominance) and mothers over 35 (perimenopause). Older parents also have had increased or prolonged exposures to environmental toxins that affect the endocrine system, another potential contributor. Having said that, my parents were teenagers when I was born, so who knows.

Whether you are XX or XY, or XXY or something else is determined at conception, when sperm combines with egg. That determines whether you are a chromosomal male or female. What gender or sexuality you identify with is something else entirely and is more of a neurodevelopmental situation. How you present physically, is a combination of genetics, but also those environmental toxins and phytoestrogens that affect the endocrine system, particularly inhibiting testosterone and enhancing estrogens within the body. Significantly lower sperm counts and testosterone levels in young men. Little girls reaching puberty at 10-12 years old. These sorts of phenomena.

A team of researchers led by Drs. Thien A. Nguyen and Katherine Roche at NIH’s National Institute of Neurological Disorders and Stroke (NINDS) explored whether differences between NLGN4 on the X and Y chromosome might play a role in some of the observed sex bias in ASD. They analyzed the genes’ activity and the proteins’ function in rat and human cells in the lab. The study was funded by NINDS and NIH’s National Institute of Mental Health (NIMH). Results were published on April 2, 2020, in Neuron.

The researchers found that the NLGN4Y protein is less able to move to the surface of cells compared with NLGN4X, making it less able to form working synapses. Neurons with only NLGN4Y showed deficits in synaptic signaling.

The researchers found that these differences in protein localization and function were due to a single amino acid on NLGN4Y. A cluster of mutations in the region surrounding that amino acid in NLGN4X have been linked to people with ASD and intellectual disability. Neurons with these mutations showed similar deficits to those seen in neurons making NLGN4Y. Further, changing the amino acid on NLGN4Y to match that of normal NLGN4X restored the protein’s function in cells.