None. No upside at all.
Actually, my experience is that AS is at the root of all my difficulties in getting a livelihood. I did have a career for about 13 years, once being a senior portfolio manager, and once setting up a hedge fund and running its investments. I was a consistently good (award winning) portfolio manager - the rarest of skills. That all came to an end over 12 years ago.
All my endeavors since have failed just as soon as other people come into the equation, and in spite of hundreds of applications for jobs I am well qualified for, and with a track record that backs it up, I have never even got a second interview, not once, and am now reduced to poverty.
When disasters happen, markets go wild and it's really difficult and stressful to look after the money. Take 9/11 - I was portfolio manager of a small hedge fund, and saw - live on TV - the second plane fly into the WTC, and it was clear the world had changed, and the market s went crazy: We could have lost our business that day and substantial amounts of our investors money. Stress, on a scale of 1 to 10? That was an 8, there, or there abouts.
But my boss coming across the floor to talk to me, any time during my career, stress, 10; called into his office? 10+. Go figure.
What I'm getting at is that the downside of not being able to find any kind of livelihood, overshadows everything else. Maybe if I had a livelihood - enough money coming in the door to pay bills and to be certain that I will be able to keep a roof over my head, then maybe the other sides: clarity of thought, knowledge, skill, attention to detail, special engaging interests etc. might be be good, but confronted with the reality of the situation, nothing.
Actually, I didn't know I had AS until I figured out that I probably had and it was the probable cause of all my difficulties, about 15 months ago, and I didn't get a formal diagnosis until 10 months ago (aged 48). Here's the one good bit to emerge from my experience: my problems were not caused by my having AS, but by my not knowing it.
Had I known, I would have pursued a different career strategy, and ended up being settled and happy in my work, well enough off, and enjoying it all. But I didn't know, and followed different strategies that could not possibly have worked, and so ended up with disastrous results.