Although I think you were both ok in "some way" for the date, from the little I know, both you and her seemed to make the wrong first impression to each other and it is obviously partially why things ended. I mean you were being you and maybe wanting some compassion or empathy or just to answer her questions perhaps or to explain your current situation or present or past health issues and struggles--and to be truthful there--whereas she was maybe caught off guard by you showing or talking of your problems so early on, thinking she deserved you putting your best foot forward and prioritizing her and wanting more positivity for at least that first date, not making excuses or not wanting you to share your problems or pain that quickly.. Coming to a date tired or not in the best mood does not seem like a recipe to have a pleasant and exciting conversation.
I just think for many, negativity or certain behavior issues shown seen early on from another is a warning sign to stay away, if not sooner then later, unless that other has strong empathy and desires to mainly support or assist which is really rare, as the other may assume you are very needy or self absorbed or things will get worse if on day one they are already wanting to share or will show problems, limitations or behavioral difficulties . Pushing too fast to be close by revealing or showing our troubles early on or to find out their views on romance and to expect much compassion shown back the first date is not the best approach, sorry, and yes your depression. Autism, or anxiety could be affecting your reasoning or thinking of the other first there, if not it is just a desire of you to not play games and be honest from the start. There is a fine line sometimes between being who we are but confoming to typical "basic" expected norms early in the relationship. If you cannot or will not mask or adapt to typical NT dating needs, you may not want to date those types, but ones who could understand more.
Attitude is everything to many. Yes there are tons of negative persons in relationships too, usually the negative with each other if that is what you want. Most dating will want more positive, functional and exciting others, so they may even play that deceiving relationship game where they say or show what the other wants to see or hear, or by focusing on the good or appropriate things to do or say while hiding the rest until later, after seeing rejection after rejection when they were mostly themselves.. And yes, talking of negatives is a turn off to most when dating. What do you offer the relationship, and what is the other interested in, as it is not just about you. What you revealed to us here focused on your health issues, so if she sensed that too, she rather not take those risks. I realize though you must have talked other more positive things though over that few hours.
Too often though on this forum I see people focused on what they want for a relationship, or not stating specifically what they want or being too unreasonable or selective there, and most importantly they are not focused on what they can give to a relationship. And they seem to push away those who gave them a chance by their attitude, rigid ways, distancing or negativity. Nobody here is owed a relationship. Yes, there are tons of people who won't give you chances, but it is partially because most of those others need something in return, and by changing at least slightly ones attitude and efforts that can make a difference to being alone or having others in our lives.
There is a reason why many with Autism have less relationship chances. I am not talking about those successful ones. Of course many people will often go for those with good jobs or money regardless of condition, even if that other is emotionally distant negative, has some deficit or seems selfish, depressed or self centered in ways. It is OK to have problems as we all do, and to share such from time to time too, but constant focus on ourselves, our problems or showing too many limitations or quirks zaps all of the energy out of others around them. Givers gave only so much time and effort to give. So, they will go to the ones who will appreciate their efforts or to the ones who they think will give up to 50% back.
I am doing fine in life. Yeah, I have had my share of health problems, past and recent, and I was alone for twenty years prior to marriage blaming everyone else, fearing or sulking, but my better attitude and efforts since helps me get past any difficulties and problems as I focus on what I can control or change, my efforts and attitude. Dwelling on the rest is wasted energy. Dwelling on other things once we learn from those experiences can get us support if we want that. But, if you want change, if those things that can be changed, or if you want not the status quo, it requires often more than that.
I personally would appreciate any and all advice and support given me regardless if I agreed, as they took the time to show care there in their ways,and as I can see good in all replies. Once we critique those people who were trying to show kindness and care, getting upset because they said or did something we were not expecting or did not want to see or hear, but then feeling entitled to express in any harsher way we desire, we are showing a desire to create separate rules for ourselves and others. If we want to be ourselves, let the others be themselves too. If we respect others' feelings though, they will be more apt to respect ours.
The answer is not for us here to tell you what you want to here, but to word things in our best way to how we feel about your situation. Each of us will have a unique perspective that you may or may not have considered before, and that may or may not benefit you but at least we are trying. It is more than reasonable for us to support or assist in the best ways we know how, not just in the manner the other feels is best, as we are allowing them to express mostly things we may or may not agree with too, without much critique there unless critiqued first.