Question: What sort of interruptions are you talking about?
If it's something like someone coming and waltzing into the room when you're trying to work, that's one thing. But if it's a small noise from somewhere that isnt important, that is a problem that needs to be worked on. One way or another, there's no way at all to completely avoid small distractions like that. They only become "interruptions" because you ALLOW them to.
And if these interruptions are happening with the sort of very high frequency that your post suggests, I'm betting that quite a few of them are small things that you dont actually NEED to pay any attention to.
One way or another, if you want to be able to do your projects at all, you have zero choice but to essentially train yourself to perform the correct steps to stop/prevent the larger interruptions (such as closing/locking a door, and putting a sign up that says "GO AWAY I'M WORKING" and maybe outright ignoring anyone that doesnt respect that... that's certainly what I do), and you need to learn to simply and totally ignore small irrelevant things. Because THOSE arent going away. There will always be small obnoxious things.
With those sorts of things, you have to say to yourself "okay, that's not something I *need* to deal with. It's not important right now. I can handle it, and I'm going to keep working even with it there". That sort of thing. Start by saying it out loud, as that can have more effect than you may think. Make it a mantra that you repeat whenever something is being annoying.
I mean, being on the spectrum makes that tougher than it would be for most people, with all the sensory issues, but still... you CAN gain control over it, but only if you go into it with the right attitude and determination. And a refusal to simply give up.
There's no avoiding the fact that this is going to take some willpower and effort on your part to deal with this overall problem.