Balls to Ultra Greedier! Ultra Greed is enough of a damage sponge as it is.
It's even worse than it sounds like.
I did a run of it just now. That mode... I know WHY they made that mode. It's because normal Greed mode is too easy, so Edmund basically went "okay" and instead of making a harder mode, made one that's basically like walking into a wall of chainsaws and giant bees.
The difficulty is outright ridiculous. That's not something that I say lightly. Most players will never even reach the final fight or get anywhere near it without getting REALLY lucky with items (many players report needing a few HUNDRED runs to get anywhere, and that's WITHOUT playing as The Lost or Keeper). It's utterly brutal from the very first floor onward. It drowns you in monsters and bullets, does things like spawn Stone Fatties (in Greed mode, since it's wave based, once they are there, they dont go away unless you kill EVERYTHING in the room before the next wave gets there), or things like having a wave that consists of two versions of The Stain (you know, the one that fires 10 squillion bullets) amongst a bunch of bouncing skulls. Oh, and you get less money overall. Because, you know, all that other stuff isnt enough.
And then there's Ultra Greed himself. His normal form is more berserk and aggressive than usual. His new golden form is... yeah, even on a lucky run, you can die so easily there. He has a bit less HP than his first form (but still a ton, and both phases total means he's as tanky as Hush), the doors can fire golden deathrays, and EVERYTHING HE DOES EXPLODES. All of his projectiles explode, summoned coins explode (and he does that like every 4 seconds, and has no wind-up time for it), and he's got this awful leaping attack, where the entire time he's in the air, special exploding coins... not the bomb coins, these fall and explode the instant they hit the ground and are WAY more numerous... fall rapidly. And then he lands and throws out shockwaves. Which explode, because of course they do. It can be hard to tell what's going on.
I'm rather convinced that only Lilith and Azazel are genuinely valid for this mode. The others? They cant deal enough damage. Lilith gets by due to her ability to multiply her damage without needing to find items, and Azazel... is Azazel. Though, I imagine Azazel probably has a few issues during that final fight, because getting that close to Ultra Greed is suicidal. Everyone else needs to get lucky with items to have enough power to even reach that final floor.... even Lilith and Azazel still need at least something of a good power boost. Enemies just come too fast and too numerous, and Ultra Greed is a war of attrition... if you dont have enough attack power, you're probably screwed. I did it with Lilith just now, and I DIDNT get lucky with items (It kept doing things like selling Mom's Stupid Range Items in the shop, or giving me weird stuff like Marked in the item rooms). I won, but it was stupidly hard.
This mode though, I cant even imagine doing this with The Lost or Keeper. Well, no... Keeper could do it if he has one of his "endless pennies" combos, which arent THAT hard to get with him. But still, it'd be absurd. That sorta thing honestly is why I just downloaded a completed save file for the game; I did the unlocks until I hit a point where they became untolerable, and then I just said screw it. I aint playing the game for the unlock system anyway, I'm playing it because it's freaking fantastic. I've never understood why so many people take a game like this, and ONLY play it until they've got all of the achievements, even the seriously pointless ones, and then they just never touch it again. Whatever happened to playing a good game because it's a good game?